Vitiligo - a kind of skin disease when the dermis loses its pigmentation naturally occurring against the background of the destruction of melanin. As a result of this process, some areas of the skin lose their color, which creates the effect of white spots or variegation topics buy accutane online.
In medical practice, in addition to the name "vitiligo", you can find another definition of this skin disease, which sounds like leucoderma. Turning to Latin, it is possible to understand the origin of this word, translated it means white skin.
As for the statistics, from vitiligo according to some estimates affects up to 1% of the population. The disease does not depend on a particular population, but more noticeable spots in dark-skinned people. Most often, the disease manifests between the ages of 10 to 30 years, for the period up to 50% of all cases of pathology.
The main symptom of the disease - is the appearance of spots on skin areas that have milky color and clearly defined boundaries. Vitiligo most susceptible part of the body such as the face (the area around the mouth, ears, eyes, nose), hands and feet (their back side, fingertips, elbows, feet, knees), groin and perianal area. The spots may appear on the hairy parts of the head, including the beard and mustache area in males.
With vitiligo is not born, it is a skin abnormality starts to form under the action of a number of factors internal and external. And rarely manifests the disease at an early age, namely 10 years. Correlations have been found with the debuting vitiligo and periods of increased solar activity in the spring and summer periods.
Autoimmune disruptions in the body are the factors that provoke the development of disease. In this case there is a failure in the functioning of the immune system and the antibodies produced to destroy foreign agents are beginning to infect healthy tissue. These findings on the relationship of vitiligo and autoimmune processes have been made based on the fact that people with skin lesions are often seen accompanying rheumatoid arthritis, thyroid disease, systemic lupus erythematosus, etc..
Communication with the genetics of vitiligo has been proven experimentally. Scientist R. Spitz, who works at the University of Colorado, found a family predisposition to the development of this skin disease. In addition, it has been scientifically proved, if a person has brown eyes, the risk of developing the disease had higher than that of owners of gray and blue eyes.
Endocrine glands. To provoke the onset of disease may be serious malfunction of the endocrine glands, as well as fluctuations in hormone levels. This group will join in neuroendocrine reasons. In addition, influence can be irregularities in the work of the pancreas, ovaries, pituitary and adrenal glands.
Violations of skin trophism, which are caused by a variety of her injuries (burns, including solar, scars and microtrauma). Vitiligo begins to form on the previously damaged areas, as these locations inflammatory reaction run having an autoimmune component. At the same time the destruction of exposed cells that produce melanin. At the same time, the more often a person exposes the skin to sunlight, the faster the process of developing depigmentation. That is trophic disorders - this is another reason for the formation of vitiligo.
Taking some drugs can provoke a pathological process.
Diseases of the liver, which leads to stagnation of bile and changes in the parenchyma of the organ that has a direct impact on the development of vitiligo.
Gastrointestinal diseases, such as goiter, maldsorbtsii syndrome. Violation enzymes absorption process leads to that the skin loses essential nutrients (zinc, copper, manganese, magnesium) for normal formation of melanin.
The impact of various chemicals on the skin. This may be substandard cosmetics, phenol and reagents containing it, formaldehyde and others.
Doctors reasonably believe that vitiligo is a powerful organism signal of trouble in general. After all, the disease often starts after past viral infections, after intoxication, after physical injury, particularly after a head injury.