Iersinioz

Iersinioz - acute zoonotic intestinal infection accompanied by toxic-allergic reaction, characterized multiochagovostyu. For iersinioza characterized by the fecal-oral route of transmission. The reservoir of infection are the cattle, rodents and dogs. Iersinioza incubation period lasts more than a week. Clinic consists of general toxic syndrome, maculopapular rash, dyspepsia; possible hepatosplenomegaly, Arthropathic syndrome of acute appendicitis, generalized form of yersiniosis buy amoxil online. Diagnosis is based on isolation of Yersinia in various biological media.

Iersinioz caused by the bacterium Yersinia enterocolitica - mobile Gram-negative facultative anaerobic rod.

Yersinia well tolerated low temperatures in a refrigerator at 4-6 ° C can not only be maintained, but also to reproduce products. (Often yersiniosis called "disease of refrigerators"). Bacteria can easily tolerate freezing and subsequent thawing, continuously stored in water, soil, but are sensitive to sunlight, drying, boiled and chemical disinfectants. Yersinia isolated enterotoxin, cytotoxins, and endotoxins.Source and reservoir are preferably iersinioza animals: various rodents, farm animals (mainly pigs) dogs. People can spread the infection, but infection of humans is rare. In the cities, the infection spread mainly rodents, it is their form clusters of epidemic foci of infection during outbreaks.

Iersinioz transmitted via the fecal-oral mechanism of food and water through. Products of animal origin, not enough heat-treated, water sources contaminated with the feces of infected animals, contribute to the implementation of infection routes. In rare cases, it realized contact-household transmission path (usually associated with low sanitary culture).

Natural person's susceptibility to iersinioza - low. Healthy people almost do not develop clinical forms of infection. Heavy and the manifest for a characteristic of children, persons suffering from immunodeficiency, chronic diseases contributing pronounced weakening of the protective properties of the organism.

Outbreaks of yersiniosis are relatively rare and most commonly occur in the mass consumption of vegetables contaminated by microbes

Iersinioz subdivided into gastrointestinal, generalized and secondary focal forms. By the gastrointestinal form include gastroenteritis, and acute ileitis thermal Yersinia appendicitis. Generalized form can take the form of sepsis, hepatitis, meningitis, pyelonephritis, pneumonia, as well as in mixed form.

Secondary focal form is divided into Yersinia arthritis, myocarditis, enterocolitis, erythema nodosum, and Reiter's syndrome. Iersinioz may be mild, moderate and severe, to acquire sharp cyclical, chronic and relapsing course.

The incubation period of intestinal yersiniosis is 1-6 days, the clinical picture is usually represented by several syndromes.

Most often marked general toxicity syndrome, which manifests itself in the form of fever, reaching 38-40 ° C, chills, headaches, general weakness, aching muscles and joints. Appetite is reduced, if severe may occur disorders of the central nervous system. Feverish period usually lasts 7-10 days (much lengthening in the case of generalized yersiniosis).

When gastrointestinal form of intoxication is usually accompanied by dyspepsia (nausea, vomiting, diarrhea, abdominal pain). In rare cases, yersiniosis rash appears. The rash maculopapular, or melkotochechnye krupnopyatnistye (sometimes ring-shaped), appear in different areas of the skin, most often in the lower part of the limb (a symptom of "socks" and "gloves"). The rash may be accompanied by a burning sensation in his hands, leaving behind areas of peeling.

In rare cases, yersiniosis rash appears. The rash maculopapular, or melkotochechnye krupnopyatnistye (sometimes ring-shaped), appear in different areas of the skin, most often in the lower part of the limb (a symptom of "socks" and "gloves"). The rash may be accompanied by a burning sensation in his hands, leaving behind areas of peeling. In some forms of yersiniosis notes Arthropathic syndrome (arthralgia). Joints of the extremities (hands, feet, elbows and knees) are painful, swollen, in the affected joints movements are limited. When generalized iersinioza can be celebrated Banti's syndrome (an enlarged liver and spleen).

In clinical practice, the most frequent form of gastrointestinal iersinioza. The disease is similar to other infectious and toxic intestinal lesions characterized primarily manifestations of intoxication and (half of) dyspepsia. Intoxication usually precedes, but can develop at the same time with dyspepsia. Sometimes this form of infection is accompanied by a rash, catarrhal or Arthropathic syndrome. Severe intoxication may contribute to the development of hepatosplenomegaly, and sometimes also indicated moderate polilimfoadenopatiya (lymph nodes are enlarged, but are painless and do not lose mobility).

Depending on the severity, duration of disease ranged from 2-3 days to two weeks or more. Long flowing intestinal yersiniosis becomes wavy character, there are signs of dehydration. Acute appendicitis or terminal ileitis with the defeat of Yersinia do not differ from those of the flow pathologies caused by non-specific flora. These conditions can both develop independently and have a secondary character, as a result of the progression of gastrointestinal or other form of infection.